PhD (m/f/x) Subject TKTD modelling based on time

Ufz - via Umantis - Busch - 29-10-2019 zur Vakanz  

Subject: TKTD modelling based on time- and dose-resolved omics data in toxicology

Project start: 1st February 2020. Working time 65% (25,35 hours per week), limited to 3 years.

Your tasks:

  • Development of a mathematical toxicokinetic-toxicodynamic (TKTD) model for the zebrafish embryo system
  • Combination of mechanistic modelling and bioinformatics
  • Integration of available data on internal chemical concentration dynamics and molecular effect dynamics for mechanistic understanding of toxicological processes

Your profile:

  • Master’s degree in Systems Biology, Modelling, Chemistry, Biology, Toxicology, Biochemistry, Biophysics, Bioinformatics or similar
  • Strong interest in modelling and working with data
  • Strong English and communication skills and interest in working in an interdisciplinary context and project
  • Skills in R, Matlab or similar are highly beneficial
  • Background in toxicology is beneficial but not required

We offer:

  • Top level interdisciplinary research at a research centre which enjoys an excellent reputation within Germany as well as internationally
  • Excellent technical facilities
  • Work in inter-disciplinary and multinational teams
  • Excellent links to national and international research networks
  • Support and optimal training courses by our graduate school (HIGRADE)
mehr...

zur Vakanz

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