Scientific Project Leader DEL
CRELUX, part of WuXi AppTec HitS, is a global provider of
structure based drug discovery solutions.
We have been delivering customized and integrated
services in drug discovery, X-ray crystallography,protein
supply, biophysical analysis, fragment and DNA-ecoded
library screenings, to support small and large molecule, as
well as biopharmaceutical drug discovery, for more than
a decade. Our mission is to enable our clients to perform
their work faster, more efficiently and more successfully.
Integrating the comprehensive portfolio of services
offered by our parent company WuXi AppTec, CRELUX
offers a unique opportunity for our collaborators to
accelerate discovery activities.
Role
DNA-Encoded Library (DEL) selection is a technology that enables fast screening of billions of small molecule compounds for drug discovery in a single Eppendorf tube. WuXi AppTec HitS has three locations which offer this service – Shanghai, Boston and Munich. Our DEL laboratory in Munich is looking to strengthen and expanding the team with a scientific Project Leader (PhD or equivalent) for a full-time position and immediate entry. As a part of innovative team, you will act as a scientific Project Leader. As a PL, you will prepare detailed scientific plan for the integrated early drug discovery projects incorporating protein production, DEL screening, biophysical and biochemical follow-up. You will need to coordinate all project-related experimental activities with the relevant stakeholders in Munich and in China. Science related project documentation and reporting, regular communication with clients and involved departments, as well as tracking and triggering troubleshooting are part of the responsibilities. Initially, 50% of your time will be dedicated to the execution of the DEL-related wet-lab experiments. We expect great diligence and accuracy during the execution of experiments, because in our experiments every single molecule counts. We are looking forward to welcome a creative, flexible and open-minded team member.
Responsibilities
- Maintaining a high-level technical knowledge (e.g., target-to-hit processes, DEL technology, protein production, biophysical and biochemical assays)
- Critical evaluation of the experimental data and potential troubleshooting
- Ensuring the timely delivery of client projects according to specified quality criteria and budget
- Providing project oversight and scientific guidance to the clients and internal teams
- Complete and timely documentation of all scientific project related data and communication
- Creation of SOPs, Working Instructions, reports and related documents
- Execution of various experimental techniques like e.g., protein quality control, SDS-PAGE, PCR, qPCR
- Reporting to the Head of DEL Lab Operations Europe
- You have PhD (or equivalent) in Life sciences (e.g., biochemistry, molecular biology or pharmacy)
- Strong project management skills, flexibility and ability to handle multiple projects in parallel
- Ability to work with internal and external stakeholders with different scientific and non-scientific backgrounds
- Ability to effectively communicate on a personal as well as on a high scientific/technical level with customers
- Fluency in English (oral and written), fluency in Chinese is an advantage
- Skilled in common computer applications (MS Office, databases, Internet applications, etc.)
- Diligence and accuracy during the execution of experiments and documentation
- Open-mind and creative problem-solving approach
A permanent contract of employment as well as an exciting and wide-ranging job in an international, innovative
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