PhD Student

Working time 65% (23,35 hours per week), limited to 3 years
to support a third party funded project with the title: Prediction of prenatal developmental toxicity in the zebrafish model – analysis of key events on the adverse outcome pathway. The zebrafish embryo will be used as the central model and based on the Adverse Outcome Pathway (AOP) concept, a proof-of-concept for an alternative testing strategy of developmental toxicity will be established. The analyses linked to AOPs include innovative, advanced automated image-based assessments of phenotypes and concentration- and time-dependent transcriptome investigations.

Your tasks:

• Independent survey and analysis of available literature
• Independent planning and conduction of laboratory exposure experiments (fish embryo test) with focus on phenotype and transcriptome assessment
• Analysis of complex data using partially automated data analysis workflows
• Active engagement in results discussion
• Presentation of results in internal/project meetings and at international conferences
• Enrolment in HIGRADE graduate school

Your profile:

• Completed master's degree in biology or a comparable discipline and interest in conducting a doctoral theses in toxicology.
• Experienced in scientific work and a keen interest in developing new fields of research within the framework of interdisciplinary cooperation.
• Able to quickly familiarize yourself with new problems and to use your own ideas.
• A high scientific standard in the evaluation, documentation and presentation of results, used to working in a project team.
• Independence, a sense of responsibility, commitment and good English language skills.
• Availability for a video conference interview including a short presentation on your background and experiences

We offer:

• Top level interdisciplinary research at a research centre which enjoys an excellent reputation within Germany as well as internationally
• Excellent technical facilities
• Work in inter-disciplinary and multinational teams
• Excellent links to national and international research networks

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